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KMID : 0363220110490121087
Korean Journal of Dermatology
2011 Volume.49 No. 12 p.1087 ~ p.1092
Cryoglobulinemia Associated with Gastric Diffuse Large B Cell Lymphoma
Jeon Su-Young

Ko Dong-Yeob
Hong Jin-Woo
Lee Ki-Yeol
Kim Ki-Ho
Song Ki-Hoon
Abstract
Cryoglobulinemia, first described by Wintrobe and Buell in 1933, is characterized by the presence of serum immunoglobulins that precipitate below 37degrees C and that dissolve on rewarming. Although the actual mechanism of cryoprecipitation and the etiology of cryoglobulinemia remains obscure, it is frequently associated with other systemic diseases, such as hepatitis C virus (HCV) infection, multiple myeloma, Sjogren¡¯s syndrome, B cell lymphoma, and systemic lupus erythematosus. No cases of cryoglobulinemia associated with B cell lymphoma have ever been published in the Korean medical literature, and few such cases have been reported in other countries. Herein, we report on a rare and interesting case of cryoglobulinemia developed in a patient with gastric diffuse large B cell lymphoma.
KEYWORD
B cell, Cryoglobulinemia, Lymphoma
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